The latest Covid-19 vaccines from Pfizer and Moderna

The latest Covid-19 vaccines from Pfizer and Moderna tend to be exceptionally effective at avoiding severe illness. Scientists are worried that if vaccinated people are silent spreaders of the virus, they could keep it circulating in their populations, putting unvaccinated people in danger. In certain respiratory infections, like the current coronavirus, the nose is the primary access stage. Vaccines are inserted directly into the tissues to activate the immune system to generate antibodies. This seems to be ample security to discourage the individual from being vaccinated from being sick.


Next-generation coronavirus vaccines can trigger immunity in the nose and the rest of the respiratory tract. Mucosal vaccinations are safer than intramuscular procedures to keep respiratory viruses from arising. The lungs are far more open than the nose or mouth to circulating antibodies. Vaccine studies did not produce results about how many patients became afflicted with the infection but showed no effects. The amount of the virus that you replicate in the nose can be decreased if one gets sick, says the immunologist. An informed guide to the global epidemic can be found at com/Heroes.


Coronavirus vaccinations demonstrate robust safety from being ill. Life can return to normal only when civilization as a whole has an inadequate defense against coronavirus. For the time being, even vaccinated citizens would continue to use masks to prevent indoor crowds. The Pfizer and BioNTech vaccines are given as an injection through the arm, as most traditional vaccines. The injection will not be any different from that one had previously, and there are no significant side effects. Moderna and Pfizer vaccines utilize a genetic molecule to activate the immune response. The enzyme, known as mRNA, is ultimately killed by the body. The mRNA is wrapped in an oily bubble that can fuse into a cell, enabling the molecule to slide in. The cell uses mRNA to produce coronavirus proteins that may activate the immune system. The mRNA will only survive for at most a few days until it is lost.

Reference
Here’s Why Vaccinated People Still Need to Wear a Mask. https://www.nytimes.com/2020/12/08/health/covid-vaccine-mask.html

4,000 active cases among inmates and 1,430 more among workers in California

More than 4,000 active cases among inmates and 1,430 more among workers in California. These are the highest numbers reported since the beginning of the pandemic. California’s cumulative number of prisoner illnesses is now more than 22,300, including 90 deaths. Hospitalizations are also at record high levels, with more than 9,900 patients throughout the state. Increasing figures are coming as local and state governments are also seeking to monitor the spread across California communities. The state governor declared a stringent regional home stay order for ICU patients this week. The state governor declared a stringent regional home stay order for ICU patients this week.
Reference
Covid-19 is raging through overcrowded California prisons. https://www.cnn.com/world/live-news/coronavirus-pandemic-12-05-20-intl/index.html

The CDC has updated its guidelines on the spread of COVID-19

The CDC has updated its guidelines on the spread of COVID-19. The CDC describes near contact as being within six feet of the person infected for 15 minutes or more during a 24-hour span. It is difficult to identify the current guidelines on which the health departments depend to perform touch tracing. The signs of the infection vary from minor symptoms to extreme illness, according to the CDC. It is not clear if the public has undergone proper instruction on proper selection and use of respiratory PPE, such as N95, for close interaction with an infectious person wearing a respiratory mask. Symptoms of the disease include: fever, chills, shortness of breath, trouble breathing, sore throat, and muscle aches, the CDC says. The disease can last 2-14 days after exposure to the virus and can be serious or moderate in some cases, it says. It is not clear if an affected person has signs for more than two days after being exposed to coronavirus, the Agency states.

Reference

CDC revises “close contact” definition. https://www.emergencyemail.org/newsemergency/anmviewer.asp?a=23565&z=58

Public health authorities and drug manufacturers need to be open regarding the side effects of coronavirus vaccine

Public health authorities and drug manufacturers need to be open regarding the side effects of coronavirus vaccines, doctors say. Doctors met with CDC advisers as states plan to administer doses as early as next month. Both Pfizer and Moderna vaccines need two doses at different intervals. Participants in the trials registered high fever, body aches, extreme headaches, day-long fatigue after the shots. “We need to make patients aware that this will not be a walk in the park,” says Dr. Sandra Fryhofer. Nurse practitioners recommend that drug manufacturers should use terms such as “response” instead of “adverse reaction” to explain side effects. “If this proves to work, people are going to toughen up,” says the nurse practitioner.

“These are immune responses,” says Stinchfield, a former member of the committee who voted. “If you feel something after vaccination, expect to feel that” Pfizer and its partner BioNTech applied for an emergency license for their coronavirus vac.

Reference

Doctors say CDC should warn people the side effects from Covid vaccine shots won’t be ‘a walk in the park’. https://www.cnbc.com/2020/11/23/covid-vaccine-cdc-should-warn-people-the-side-effects-from-shots-wont-be-walk-in-the-park-.html

Patients with Type O or B blood spent less time in ICU than those with Type A or AB

Study: Patients with Type O or B blood spent less time in ICU than those with Type A or AB. They were also less likely to require ventilation and to have kidney failure. Study looked at 95 critically ill COVID-19 patients at hospitals in Vancouver, Canada, between February and April. Researchers did not see any link between blood type and the length of each patient’s total hospital stay.  Both new studies came out Wednesday in the journal Blood Advances.     

Reference

https://www.sciencealert.com/study-gives-more-evidence-that-blood-type-may-change-covid-19-risk-and-severity

COVID-19 assaults our immune system

In an isolated laboratory at the Icahn School of Medicine in Mount Sinai, East Harlem, virologist Benjamin never has been able to decipher how the virus that causes COVID-19 assaults our immune system, wreaking havoc like no other virus he has ever examined.

Every cell of our body shares the same DNA and single-strand RNA, which functions like a machine programming the cell to generate proteins, according to New Yorker. SARS-CoV-2 disrupts programming by replacing 60 percent of this software in every cell it infects. Just 1% of the RNA in each cell is replaced by a normal virus.

The novel coronavirus shuts down just one arm of our immune system — the one that alerts other cells to protect themselves from viral spread — while leaving the other arm to run wild. In comparison to other viruses, SARS-CoV-2 does not modulate the second immune response that sends cytokines across the body to summon white blood cells.

Reference
Researchers Discover How COVID-19 Attacks Our Immune …. https://www.newsmax.com/health/headline/immune-system-cytokine-storm-viral-spread/2020/11/03/id/995070/.

It has been more than 300 days since Chinese authorities first told the World Health Organisation

It has been more than 300 days since Chinese authorities first told the World Health Organisation that Wuhan residents were sick with a mysterious virus. Scientists discovered soon what the virus was (a coronavirus) and what it did (make people ill with a disease called COVID-19), and it spread across the globe like flames.

More than 1 million people have died worldwide, hundreds of thousands get sick every day, and the United States is the world’s most significant disease.

Researchers were still unsure how the virus spread, why people were infectious, or whether one could get it twice when we released our first guide to the coronavirus. These questions may have some residual confusion, but scientists have made some remarkable strides in responses.

Reference
The global death toll from COVID-19 surpasses 1 million – CNET. https://www.cnet.com/health/global-death-toll-from-covid-19-surpasses-1-million/

Some Covid-19 patients experience a long-lasting skin issues following the infection

Some Covid-19 patients experience a long-lasting skin issues following the infection, researchers from Massachusetts General Hospital are finding, including rashes, hives, and “Covid toes,” underpinning previous, limited research about a collection of new symptoms connected with Covid-19 and yet another troubling sign that for a few the herpes virus could have an enduring impact.

The research unearthed that some patients reported skin issues for as much as five months, though an average of patients only experiences observable symptoms for 12 days.

This set of Covid-19 symptoms contributes to mounting evidence that, for a few, the illness may be a long haul — lots of people are now calling this the “long Covid.”

Symptoms varied in severity, though generally mild, researchers said, you need to include rashes, hives, and chilblains, the very last of that your researchers have termed “Covid toes.”

The findings that have been presented in the EADV Virtual congress Thursday and result from studying the info of nearly 1,000 long Covid cases in 39 different countries may help scientists comprehend the body’s inflammatory reaction to Covid-19 infection.
Reference
‘Covid Toes,’ Rashes, And Hives: New Research Underpins …. https://www.forbes.com/sites/roberthart/2020/10/29/covid-toes-rashes-and-hives-new-research-underpins-covid-19s-long-term-skin-impact/

The spread of the Covid-19 among members in a family group

The spread of the Covid-19 among members in a family group after one individual is infected is “common” and occurs quickly after illness onset, relating to new research through the US Centers for Disease Control and Prevention.

The person exposed or suspected of experiencing Covid-19 should always be isolated before getting tested, and before test outcomes get back to protect others in the home, said the analysis, published Friday when looking at the CDC’s Morbidity and Mortality Weekly Report.

“Because prompt isolation of persons with #COVID-19 can lessen household transmission, persons who suspect which they could have COVID-19 should isolate, stay in the home, and employ an independent bedroom and bathroom if feasible,” wrote a CDC-led team of researchers.
All people in family members should also wear masks all of the time per space, the group said.

Referencehttps://www.cnn.com/2020/10/30/health/household-spread-covid-19-wellness/index.html
Household spread of Covid-19 is common and quick, a new CDC study finds. https://www.cnn.com/2020/10/30/health/household-spread-covid-19-wellness/index.html.

Regeneron Pharmaceuticals has paused critically ill COVID-19 patients’ enrollment

Regeneron Pharmaceuticals has paused critically ill COVID-19 patients’ enrollment with its trial studying the antibody cocktail treatment, which was fond of President Trump earlier this month. The choice is because of potential safety concerns.
The drugmaker on Friday said it was suspending the enrollment of hospitalized #COVID-19 patients requiring high-flow oxygen or mechanical ventilation after an unbiased monitoring committee observed “a potential safety signal and an unfavorable risk/benefit profile at the moment.”

The enrollment of individuals in this category should be on hold, pending the collection and evaluation of additional data.

Trials continue to test the antibody cocktail in hospitalized patients necessitating little if any extra oxygen. Other trials involving mild or moderately ill patients also can move ahead.

The drug has revealed encouraging outcomes. Regeneron on Wednesday said early data confirmed the therapy lowered COVID-19 related medical visits by 57 percent.

Regeneron earlier this month asked the foodstuff and Drug Administration for emergency approval and said it could make doses accessible to the American people free of charge. The drugmaker said it might have sufficient doses for 300,000 people when looking at the coming months.

Reference

Regeneron stops enrolling critically ill COVID-19 patients …. https://news.immitate.com/2020/10/30/regeneron-stops-enrolling-critically-ill-covid-19-patients-for-antibody-drug-trial-thehill-the-hill/.