4,400 Modern Doses of Vaccine Not Kept Cool

4,400 Modern Doses of Vaccine Not Kept Cool Enough Might be Unusable. Maine health officials noticed that during transport, several Moderna vaccine shipments were not kept sufficiently cool. According to the CDC, Moderna’s vaccine vials must stay at freezing temperatures between -25°C and -15°C. Whether the doses of the vaccine would have to be tossed away or even be used is uncertain. The vaccine was shipped from the manufacturer’s processing plant in Massachusetts to 50 locations throughout the state, health officials said. Processes are to guarantee that the doses are held cool, the U.S. Centers for Disease Control and Prevention reports.

Resource
4,400 Moderna Vaccine Doses Not Kept Cold Enough May Be Unusable. https://www.npr.org/2021/01/19/958539556/4-400-moderna-vaccine-doses-not-kept-cold-enough-may-be-unusable

Filter-less coffee contain higher amounts of cafestol and kahweol

These types of filter-less coffee contain higher amounts of cafestol and kahweol, which are found in oil droplets floating in the coffee and the sediment, Lisa Drayer, RD, told CNN. Drip coffee is already known to raise triglyceride and LDL cholesterol (bad cholesterol) levels. Drink filtered (paper) coffee to reduce the levels. For the research document published in The European Journal of Preventive Cardiology, the researchers began to investigate whether any particular brewing method for coffee was associated with a higher risk of premature death, heart disease, and stroke.

People who drank between one and four cups every day had the lowest death rates overall, including abstainers.

The study analyzed claims that the moderate consumption of unfiltered coffee is beneficial.

The theories regarding the connection between coffee and reduced risk of Alzheimer’s disease and Parkinson’s disease abound among scientists.

According to a Harvard School of Public Health study, drinking coffee causes a lowered risk of depression in women.

If you want to be well informed of your favorite morning beverage, make sure you are fully informed of coffee.

Reference

The Most Dangerous Way to Drink Your Coffee, According to Science. https://www.eatthis.com/the-most-dangerous-way-to-drink-your-coffee-according-to-science/

Health experts say that at least 70 percent of the country needs to be vaccinated

Health experts say that at least 70 percent of the country needs to be vaccinated to ensure herd immunity and completely eradicate the epidemic that killed more than 300,000 Americans. National polls show a growing number of Americans are willing to get a coronavirus vaccine, but some populations, especially Black and Latinos, are reticent. Federal officials are releasing a 95 percent effective vaccine from Pfizer and BioNTech, and on Friday the Food and Drug Administration cleared a second vaccine from Moderna that was almost equally effective in preventing COVID-19 cases. Some people have quoted what the Trump administration calls politicizing a vaccine, despite officials’ denial that policy plays a role in rapid development.

These groups have been reinforced by the coronavirus epidemic, which both eroded trust in traditional institutions and left millions of people with few options for social interaction beyond the internet. Paul Barrett, deputy director of the Stern Center for Business and Human Rights at New York University, told The Hill that the biggest source of coronavirus vaccine disinformation is “the transformation of long-standing anti-vaccine activists. “There is a considerable foundation that existed before anyone heard of COVID-19,” he explained. The same mistrust in institutions that have revived anti-vaccination communities has also led thousands to conspiracy theories.

QAnon, whose followers believe President Trump is trying to expose a dark elite group running child sex trafficking gangs in the media and government, has had a clear benefit of shifting towards this conspiratorial notion. The growth of QAnon may make it difficult to achieve herd immunity as its supporters increase the lies about COVID-19 vaccines, as it is applied with a microchip to control and monitor citizens or Bill Gates is responsible for the coronavirus. “These conspiracy theories are wrong, but I am very concerned that they could enter the mainstream. And if we have people who will not be vaccinated, this makes it much more difficult for us to achieve herd immunity through vaccination and therefore end the epidemic, ”said Leana Wen.

A recent Kaiser Family Foundation survey revealed that 42 percent of Republicans would likely not be or definitely would not be vaccinated against the coronavirus. Vice President Pence and his wife Karen were vaccinated live on television Friday in an attempt to bridge the partisan gap. “Today there are millions of Americans whose most trusted envoy is President Trump. And that’s why it’s really important for President Trump to speak to correct misinformation, ”Wen said.

Trump has repeatedly raised doubts about the seriousness of the epidemic and mocked his use of masks to limit its spread. According to a report from Cornell University, 38 percent of all articles published in January that contained misinformation about the coronavirus outbreak, lawmakers in Congress supporting Trump also said things that could deter vaccine use. Ken Buck said in a Fox Business interview Friday morning that he would not receive the vaccine because he was “more concerned with the illness about the side effects of the vaccine”.

His office later announced that Buck believes people at risk should “get the vaccine immediately”. Right-wing media has also been the driving force of coronavirus misinformation. Beyond restricting current coronavirus misinformation, Barrett said platforms should work to increase information about vaccines from trusted sources. Still, healthcare professionals said tech companies can only go so far.

Reference

Health officials, social media scramble to fight vaccine misinformation. https://thehill.com/policy/technology/530943-health-officials-social-media-scramble-to-fight-vaccine-misinformation

The diversional practice helps individuals to overcome the challenges and problems

The diversional practice helps individuals to overcome the challenges and problems in their everyday lives, and in some instances, to even reach an optimum existence outside the defined realities of time and space — a condition we term “flow.” Occupation can redirect citizens away from the difficulties of their lives toward happiness and positive participation. Habits have been found to improve knowledge, decrease exhaustion, free focus, and defend individuals against the stressful consequences of challenging conditions. During daunting situations, the profession provides the opportunity for a richer, more cohesive self after the crisis settles.

Reference
Seven constructive ways to get through the Covid-19 pandemic.https://www.cnn.com/2020/12/18/health/constructive-activities-covid-pandemic-wellness-partner/index.html

One week after obtaining a federal green light from Pfizer and BioNTech’s COVID-19 vaccine

On Friday, only one week after obtaining a federal green light from Pfizer and BioNTech’s COVID-19 vaccine, the Food and Drug Administration officially approved a second emergency vaccine—this one produced by Moderna. The vaccine produced by Moderna, whose headquarters in Cambridge, Mass., has been given an immediate usage permit by federal regulators. The vaccine produced by Moderna, whose headquarters in Cambridge, Mass., has been given an immediate usage permit by federal regulators. FDA Authorizes Moderna COVID-19 Vaccine For Emergency Use: Coronavirus Changes Food and Drug Administration greenlights the U.S. biomedical firm’s emergency vaccine. The step bolsters a massive inoculation campaign already underway.With last week’s Pfizer vaccine permit, health and defense authorities have undertaken a vast campaign to deliver millions of doses throughout the world. Amid the flurry accompanying the rollout of the Pfizer vaccine, Moderna’s alternative made steady headway in its drive toward a permission.

Reference
Moderna’s COVID-19 Vaccine Becomes 2nd To Earn FDA Authorization.https://www.npr.org/sections/coronavirus-live-updates/2020/12/18/947948227/modernas-covid-19-vaccine-becomes-2nd-to-earn-fda-authorization?refresh=true

Pfizer will only be able to deliver 2.9 million doses in the first few days

It is expected that Pfizer will only be able to deliver 2.9 million doses in the first few days and only up to 6.4 million doses by 19 December, according to Operation Warp Speed, the government’s vaccine effort.

“As part of the discussion on who should qualify for phase 1b access to the vaccine, ACIP has so far discussed individuals with high-risk medical conditions such as cancer, chronic kidney disease, chronic obstructive pulmonary disease (COPD), immunocompromised organ transplant status, obesity, severe heart disease, sickle cell disease, and type 2 diabetes,” said the Muscular Dystrophy Association.

For example, last month, the head of the Hawaii Healthcare Association told CNN that not a single hospital in Hawaii had a freezer that could remain cold enough to store Pfizer’s coronavirus vaccine and that the state may not have enough access to dry ice to make proper use of the company’s distribution boxes.

They resolve quickly, but CDC and other officials are worried that they might scare some people away from getting a second dose of vaccine and are preparing educational materials to let people know the symptoms are a sign that the vaccine is working to reactivate the body’s immune response and is harmless.

Vaccine counselors have already broken down priority groups into subgroups, and only the first people to receive vaccines have been identified.

Operation Warp Speed Chief Counselor Moncef Slaoui has projected that Pfizer and Moderna can make and deliver between 60 million and 70 million vaccines in January and hopes that two other vaccine makers, AstraZeneca, and Johnson & Johnson, will join the vaccine mix in the coming months.

Moderna and Pfizer each claim that they can take up to a billion doses by the end of 2021, but Moderna say that it could be half that—a product that has never been sold before—and Pfizer has already severely adjusted its timeline for delivery of vaccines after unspecified manufacturing problems.

Slaoui said that up to 15% of Pfizer and Moderna vaccine participants had quite noticeable side effects,” including nausea, body aches, headaches, and chills.

Pfizer’s vaccine had its first scare in the US with a health worker in Juneau, Alaska, suffering from an allergic reaction.

“Around one in every million people who get a vaccine can have a severe allergic reaction to the vaccine,” Dr.

And what about the essential workers? ACIP’s expert bodies, including Johns Hopkins University and the National Academies of Science, Engineering, and Medicine, suggest it will be prudent to vaccinate those who work in food processing, emergency responders, and service workers before the general public.

The US Food and Drug Administration granted emergency use authorization for Pfizer and BioNTech’s vaccine on Friday, and it is widely expected that EUA will give a similar vaccine to Moderna next week.

Reference

Trump says he is ‘not scheduled’ to take Covid-19 vaccine …. https://www.rt.com/usa/509567-trump-white-house-vaccine-later/

The latest Covid-19 vaccines from Pfizer and Moderna

The latest Covid-19 vaccines from Pfizer and Moderna tend to be exceptionally effective at avoiding severe illness. Scientists are worried that if vaccinated people are silent spreaders of the virus, they could keep it circulating in their populations, putting unvaccinated people in danger. In certain respiratory infections, like the current coronavirus, the nose is the primary access stage. Vaccines are inserted directly into the tissues to activate the immune system to generate antibodies. This seems to be ample security to discourage the individual from being vaccinated from being sick.


Next-generation coronavirus vaccines can trigger immunity in the nose and the rest of the respiratory tract. Mucosal vaccinations are safer than intramuscular procedures to keep respiratory viruses from arising. The lungs are far more open than the nose or mouth to circulating antibodies. Vaccine studies did not produce results about how many patients became afflicted with the infection but showed no effects. The amount of the virus that you replicate in the nose can be decreased if one gets sick, says the immunologist. An informed guide to the global epidemic can be found at com/Heroes.


Coronavirus vaccinations demonstrate robust safety from being ill. Life can return to normal only when civilization as a whole has an inadequate defense against coronavirus. For the time being, even vaccinated citizens would continue to use masks to prevent indoor crowds. The Pfizer and BioNTech vaccines are given as an injection through the arm, as most traditional vaccines. The injection will not be any different from that one had previously, and there are no significant side effects. Moderna and Pfizer vaccines utilize a genetic molecule to activate the immune response. The enzyme, known as mRNA, is ultimately killed by the body. The mRNA is wrapped in an oily bubble that can fuse into a cell, enabling the molecule to slide in. The cell uses mRNA to produce coronavirus proteins that may activate the immune system. The mRNA will only survive for at most a few days until it is lost.

Reference
Here’s Why Vaccinated People Still Need to Wear a Mask. https://www.nytimes.com/2020/12/08/health/covid-vaccine-mask.html

Public health authorities and drug manufacturers need to be open regarding the side effects of coronavirus vaccine

Public health authorities and drug manufacturers need to be open regarding the side effects of coronavirus vaccines, doctors say. Doctors met with CDC advisers as states plan to administer doses as early as next month. Both Pfizer and Moderna vaccines need two doses at different intervals. Participants in the trials registered high fever, body aches, extreme headaches, day-long fatigue after the shots. “We need to make patients aware that this will not be a walk in the park,” says Dr. Sandra Fryhofer. Nurse practitioners recommend that drug manufacturers should use terms such as “response” instead of “adverse reaction” to explain side effects. “If this proves to work, people are going to toughen up,” says the nurse practitioner.

“These are immune responses,” says Stinchfield, a former member of the committee who voted. “If you feel something after vaccination, expect to feel that” Pfizer and its partner BioNTech applied for an emergency license for their coronavirus vac.

Reference

Doctors say CDC should warn people the side effects from Covid vaccine shots won’t be ‘a walk in the park’. https://www.cnbc.com/2020/11/23/covid-vaccine-cdc-should-warn-people-the-side-effects-from-shots-wont-be-walk-in-the-park-.html

Both the Pfizer vaccine and the Moderna vaccine were developed with new technology

Both the Pfizer vaccine and the Moderna vaccine were developed with new technology that uses messenger RNA. Neither Pfizer nor Moderna has reported any serious safety issues in their trials so far. An independent group of advisers will review vaccine data to the FDA and the CDC. The FDA will decide whether to grant authorization for emergency use; then, the CDC will decide who gets the vaccine. The advisory committees do not have the authority to make decisions, but they follow other groups’ recommendations, Salmon says. The decision does not end at the time of recommendation, Lee says. “We are always in creating new data as it emerges, so it can ch so that,” she says. Back To the pageYou came from: The page you were from. The CDC will craft guidance for the CDC about prioritizing, who receives the vaccine. First, Salmon said.


The public will view trial data and observe discussions as the Vaccines and Related Biological Products Advisory Committee conducts its review in early December. “It will include public deliberation, and that is a good thing,” Salmon said. Salmon added that this type of transparency would be a crucial way to bolster public trust and combat misinformation. This is particularly important because the pandemic has become heavily politicized.


Reference
Will the Covid vaccine be safe? What the scientists want to see.https://www.nbcnews.com/health/health-news/will-covid-vaccine-be-safe-what-scientists-want-see-n1248466
What is mRNA? How Pfizer and Moderna tapped new tech to …. https://www.nbcnews.com/science/science-news/what-mrna-how-pfizer-moderna-tapped-new-tech-make-coronavirus-n1248054
What Is Homework’s Purpose in a Pandemic?. http://www.ascd.org/publications/newsletters/education-update/oct20/vol62/num10/What-Is-Homework’s-Purpose-in-a-Pandemic%C2%A2.aspx

Interleukin-1 has been involved as a mediator of chronic pericarditis

Interleukin-1 has been involved as a mediator of chronic pericarditis. A phase 3 trial of rilonacept was performed in patients with acute symptoms and systemic inflammation. During the run-in period, the median time for pain resolution or near-resolution was 5 days, and the median time for normalization of CRP was 7 days. Injection site reactions and upper respiratory tract infections were the most common adverse events. Among patients with chronic periecarditis, treatment resulted in rapid resolution and a slightly lower risk of recurrence than placebo. The most common side effects were injection site reactions and upper respiratory tract infections.

Reference

Phase 3 Trial of Interleukin-1 Trap Rilonacept in Recurrent Pericarditis. https://www.nejm.org/doi/full/10.1056/NEJMoa2027892