Tag Archives: vitamin D

A significant effect on the risk of type 1 diabetes

European vitamin D deficiency has limited effects on the likelihood of type 1 diabetes. Type 1 diabetes is an inflammatory disorder in which the body’s capacity to metabolize glucose is compromised. Worldwide, the incidence of this disease under the age of 14 is projected to increase by 3% per year. There are no drugs proven to be able to help prevent type 1 diabetes. According to the American Diabetes Foundation, over 1.6 million Americans have diabetes.

There does not seem to be a significant impact of vitamin D on type 1 diabetes, although smaller effects can occur. Even though it cannot be ruled out that decreased amounts of lifelong calcitriol, an active source of vitamin D, could be correlated with the condition, the study’s results left open the possibility. The researchers state, “they” before more data from major randomized control trials suggest that vitamin D supplementation cannot be used as a preventative measure.

References

Low Vitamin D Levels In Europeans Does Not Raise Risk Of …. https://www.forbes.com/sites/anuradhavaranasi/2021/02/28/low-vitamin-d-levels-in-europeans-does-not-raise-risk-of-type-1-diabetes-study-shows/

Vitamin D levels and risk of type 1 diabetes: A Mendelian …. https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1003536

Over 80 percent of 200 COVID-19 sufferers in a hospital in Spain have vitamin D deficiency

Over 80 percent of 200 COVID-19 sufferers in a hospital in Spain have vitamin D deficiency, relating to new research published when looking at the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.

Vitamin D is a hormone the kidneys generate that manages blood calcium amount and impacts the immune protection system. Vitamin D deficiency happens to be connected to many health problems, although scientific studies are still underway into why the hormone impacts other systems regarding the body. Many studies point out the beneficial affectation of vitamin D on the immune protection system, especially about protecting infections.

“One approach is always to identify and treat vitamin D deficiency, particularly in high-risk individuals, for instance, the elderly, patients with comorbidities, and nursing home residents, who will be the key target population for the COVID-19,” said study co-author José L. Hernández, Ph.D., regarding the University of Cantabria in Santander, Spain. “Vitamin D treatment should always be recommended in COVID-19 patients with lower levels of vitamin D circulating when you look at the blood because this approach could have beneficial effects both in the musculoskeletal in addition to the immune protection system.”

The investigators found that 80 percent of 216 COVID-19 patients in the Hospital Universitario Marqués de Valdecilla had vitamin D deficiency, and men had lower vitamin D levels than women. COVID-19 patients with reduce vitamin D levels also had increased serum amounts of inflammatory markers such as ferritin and D-dimer.
Reference
Over 80% of Hospitalized COVID-19 Patients Have Vitamin D Deficiency, Study Finds. https://scitechdaily.com/over-80-of-hospitalized-covid-19-patients-have-vitamin-d-deficiency-study-finds/

Do you believe that Vitamin D can reduce the impact of Covid-19?

The research shows that Supplement D helps to reduce the chance of infection by FIFTY-FOUR percent.

Vitamin D reduces half the chance of dangerous coronavirus complications, based on an innovative new study.

Earlier this season, research recommended that COVID-19 individuals with high vitamin D amounts were more prone to survive the condition. However, U.K. health authorities responded by saying back June that there was insufficient evidence to claim that getting vitamin D dietary supplements, which is needed for bone tissue, muscle, and tooth wellness, can prevent or decrease the risk of coronavirus.

However, a new analysis led by Dr. Michael Holick from Boston University’s College of Medicine offers discovered that the product can reduce the threat of being contaminated with COVID-19 and decreases the probability of a patient experiencing fatal complications, using the experts claiming that vitamin D sufficiency will be associated with a reduced degree of inflammatory markers and increased blood degrees of immune cells.

“Because vitamin D deficiency and insufficiency is widespread in kids and adults within the U.S. and globally, especially in the wintertime months, it is prudent for everybody to take a supplement D supplement to lessen the risk of becoming infected and getting problems from COVID-19,” he recommended.

For the analysis, Holick’s team took blood examples to gauge the vitamin D levels of 235 sufferers admitted to the hospital with COVID-19, and the severe nature of this infection was monitored. They found that in patients more than 40, those with sufficient degrees of supplement D were a lot more than 51 less inclined to pass away from coronavirus.

In another study directed by Dr. Holick, the researchers discovered that the supplement could reduce the risk of infection because they discovered that adequate vitamin D could decrease the threat of catching COVID-19 by 54%.

Reference

Vitamin D can reduce the impact of Covid-19.https://www.emergencyemail.org/newsemergency/anmviewer.asp?a=23303&z=58

Vitamin D alone does not prevent fractures, a new study finds!

Taking calcium and vitamin D could help older adults curb the chance of a bone fracture, but vitamin D alone doesn’t finish the job, a brand new research review concludes.

The analysis of 28 past studies found that senior citizens with higher blood methods of vitamin D were reluctant to suffer a broken hip or other fracture over five to 15 years.

The picture was different in various research that tested the effects of using vitamin D supplements: They found no evidence that vitamin D alone reduced older adults’ chance of fractures.

In comparison, trials that tested mixed calcium and vitamin D showed modest protective effects.

“Combined treatment with both of your calcium and vitamin D reduced the potential risk of hip fracture by one-sixth, which resulted in being harmed more beneficial than taking standard doses of vitamin D alone,” said senior researcher Dr. Robert Clarke, a professor of epidemiology and public health medicine along at the University of Oxford in England.

The findings, published online Dec. 20 in JAMA Network Open, aren’t the last word on vitamin D and fractures. Some ongoing trials are testing high-dose vitamin D in people who are at increased danger of bone breaks.

But for now, there may be no proof that it works by Clarke.
In the United States alone, about 54 million people have deep bone tissue or outright osteoporosis—the brittle-bone disease that could bring about fractures, as per the National Osteoporosis Foundation (NOF). It’s estimated that after age 50, much fewer women and one-quarter of males will break a bone as a consequence of osteoporosis.

Calcium is essential to building and maintaining healthy bones, while vitamin D assists the body in absorbing calcium and supports the muscle function needed to avoid falls.

Though when looking at preventing fractures in people with osteoporosis, there’s only so much that supplements can do, said the NOF’s, Beth Kitchin. She wasn’t involved with the study.

“The expectation that vitamin D and calcium, alone, will prevent fractures is likely unrealistic,” said Kitchin, who’s also another person professor of nutrition sciences for the University of Alabama at Birmingham.

To assist preserve bone health go away with muscles strong; people need regular exercise by Kitchin. The activity that will make our bodies move against gravity while staying upright—like jogging, jumping rope, or dancing—can help support bone density. And use that builds muscle strength or improves balance can help lower the chance of falls.

Avoiding smoking and alcoholism is also critical to preventing bone loss, as stated by the NOF.

Once osteoporosis is diagnosed, medications—which either slow bone breakdown or boost bone formation—may be necessary, Kitchin said. “Fall-proofing” your room is another essential step. Meaning getting rid of tripping hazards in and out of the house; installing grab bars in bathrooms; maintaining stairways well lit, among other measures.

Of the studies, Clarke’s team analyzed, 11 were observational. They followed older adults among the “practical,” tracking fracture rates anywhere from five to fifteen years. Overall, the upper a person’s blood stages of vitamin D were at the outset, the lower the potential risk of fracture.

“But that doesn’t prove cause and effect,” Kitchin stressed. “High vitamin D levels are most certainly a marker of something else entirely.”

Few foods contain vitamin D, she noted. Instead, the human body synthesizes it whenever the skin is exposed to sunlight. So people with high vitamin D levels may spend a lot of time outdoors, for example.

The review included too 11 trials testing vitamin D alone, and six testing vitamin D and calcium. Study participants’ average age ranged from 62 to 85, and they were followed for as much as five years.

Overall, people gave calcium, and vitamin D had a 16% lower likelihood of hip fracture than those given placebos or no treatment. Their danger of any bone break was 6% lower.

So how should you know if it is recommended to take supplements? You can ask your doctor to measure your blood level of vitamin D, to detect any deficiency, Kitchin said. As regards to calcium, she added, “evaluate your diet plan.”

If you are genuinely avoiding food much dairy, green veggies, and foods fortified with calcium, you would possibly need to have a supplement.

According to the NOF, adults younger than 51 should strive for 1,000 mg of calcium a day; afterward, the advice surges to 1,200 mg. As for vitamin D, people newer 50 should force 400 to 800 international units (IU) daily, while mature workers need 800 to 1,000 IU.

The advice on vitamin D does vary, however, with some more groups recommending more. As per the Institute of Medicine, the safe upper limit of vitamin D is 4,000 IU daily for the majority of grown-ups.

Author Resource Box:
Vitamin D Alone Doesn’t Prevent Fractures, New Study Finds …. https://www.usnews.com/news/health-news/articles/2019-12-20/vitamin-d-alone-doesnt-prevent-fractures-new-study-finds

6 Surprising Spirulina Benefits Your Doctor Doesn’t Know …. https://yurielkaim.com/6-surprising-spirulina-benefits/

Vitamin D alone doesn’t prevent fractures, new study finds. https://medicalxpress.com/news/2019-12-vitamin-d-doesnt-fractures.html

It is interesting that Vitamin D supplement does not prevent type 2 diabetes in adults at high risk, study finds

Taking a daily vitamin D supplement will not prevent type 2 diabetes in adults at high risk, according to results from research funded by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), an element of the National Institutes of Health. The Vitamin D and Type 2 Diabetes (D2d) study enrolled 2,423 adults and was conducted at 22 sites throughout the united states of America. These findings were published June 7 into the New England Journal of Medicine and presented during the 79th Scientific Sessions regarding the American Diabetes Association in San Francisco bay area.

2d may be the most extensive study to directly examine if daily vitamin D supplementation assists in maintaining people at high risk for type 2 diabetes from developing the illness. The analysis included adults aged 30 or older and assigned participants randomly to either take 4,000 International Units (IU) for the D3 (cholecalciferol) kind of vitamin D or a placebo pill daily. All study participants had their vitamin D levels measured at the beginning of the study. During those times, about 80% of participants had vitamin D levels considered sufficient by U.S. nutritional standards.

“Observational studies have reported an association between lower levels of vitamin D and increased risk for type 2 diabetes,” said Myrlene Staten, M.D., D2d project scientist at NIDDK. “Additionally, smaller studies discovered that vitamin D could improve the function of beta cells, which produce insulin. However, whether vitamin D supplementation might help prevent or delay type 2, diabetes had not been known.”

The analysis screened participants every three to half a year for an average of 2.5 years to ascertain if diabetes had developed. Researchers then compared how many people in all the two study groups which had progressed to type 2 diabetes. At the end of the analysis, 293 away from 1211 participants (24.2%) in the vitamin D group developed diabetes in comparison to 323 out of 1212 (26.7%) into the placebo group – a difference that failed to reach statistical significance. The study was made to detect a risk decrease by 25% or even more.

D2d enrolled a different number of participants with a variety of physical characteristics, including sex, age, and body mass index, as well as racial and ethnic diversity. This representation helps ensure that the analysis findings could be widely applicable to people at high risk for developing type 2 diabetes.

As well as the study’s size, certainly one of its major strengths could be the diversity of their participants, which enabled us to examine the effect of vitamin D across a sizable number of people. When the study ended, we found no meaningful difference between the two groups, no matter age, sex, race, or ethnicity.

Reference
NIH-funded trial finds vitamin D does not prevent type 2 …. https://www.nih.gov/news-events/news-releases/nih-funded-trial-finds-vitamin-d-does-not-prevent-type-2-diabetes-people-high-risk

Be aware of vitamin D deficiency

Vitamin D deficiency means that you are not getting enough vitamin D to stay healthful.

Calciferol helps the body to absorb calcium supplements. Calcium is among the main foundation of bone. Supplement D also provides a job in the anxious, muscles, and proof systems.

You can obtain vitamin D in 3 ways: through your skin layer, from your diet, and health supplements. Your body forms vitamin Deb naturally after exposure to sunshine. However, too much sun publicity can lead to skin aging and pores and skin cancer, so many people try to get their vitamin D from additional sources.

The amount of vitamin D you need each day depends on your age. The recommended amounts, in worldwide models (IU), are:

  • Delivery to 12 weeks: four hundred IU
  • Children 1-13 years: 600 IU
  • Teens 14-18 years: 600 IU
  • Individuals 19-70 years: 600 IU Adults 71 years and older: 800
  • Conceived and breastfeeding women: six-hundred IU
  • People at risk of vitamin D insufficiency might require more. Consult with your health treatment provider about how exactly much you may need.

What can cause vitamin D deficiency?
You may become deficient in calciferol for different reasons:

  • You do not receive more than enough vitamin D in what you eat
  • An individual absorb more than enough vitamin D via food (a malabsorption problem)
  • You do not get enough contact with sunlight.
  • Your liver or perhaps kidneys cannot convert calciferol to its dynamic kind in your body.
  • You take drugs that hinder your body’s capability to convert or absorb supplement D
  • Who is vulnerable to vitamin D deficiency?
  • Some people are at more substantial risk of vitamin D deficiency:
  • Breastfed infants, since human take advantage of is a poor source of vitamin D. If you are breastfeeding, give your infant a supplement of four hundred IU of vitamin Deb every day.
  • Older adults, since your skin, do not make vitamin D when exposed to sunshine as efficiently as you were young, and your kidneys are less able to convert vitamin D to the active form.
  • People with dark skin, which includes less capacity to make vitamin D from sunlight.
  • People with disorders such for example Crohn’s disease or celiac disease who do not deal with body fat properly, because vitamin D requirements fat to end up being consumed.
  • People who have weight problems, because all their surplus fat binds to some supplement D and prevents that from engaging in the blood.
  • Those who have had gastric bypass surgery
  • People with brittle bones
  • People who have chronic kidney or perhaps liver disease.
  • People who have hyperparathyroidism ( an excessive amount of a hormone that handles your body’s calcium level)
  • People who have sarcoidosis, tuberculosis, histoplasmosis, or various other granulomatous diseases (a disease with granulomas, selections of cells due to severe inflammation)
  • People with some lymphomas, a type of cancer.
  • People who consider medicines that affect vitamin D rate of metabolisms, such as cholestyramine (a cholesterol drug ), anti-seizure medicines, glucocorticoids, antifungal medicines, and HIV/AIDS medications.
  • Talk with your health care provider if you are at risk for vitamin D insufficiency. There is a blood test which can measure how much vitamin D is in your body.

What complications does vitamin D deficiency trigger?
Vitamin D insufficiency can result in a reduction of bone relative density, that may donate to osteoporosis and bone injuries.

Severe vitamin D insufficiency could also result in other diseases. Found in kids, it can trigger rickets. Rickets can be an uncommon disease that triggers the bone fragments to be smooth and fold. African American infants and children are at higher risk of getting rickets. In adults, severe vitamin D deficiency leads to osteomalacia. Osteomalacia causes weak bones, bone pain, and muscle weakness.

Researchers are studying vitamin D for its possible connections to several medical conditions, including diabetes, high blood pressure, cancer, and autoimmune conditions such as multiple sclerosis. They need to do more research before they can understand the consequences of supplement D on these circumstances.

How do I get more supplement D?
Some foods involve some vitamin D:

  • Fatty seafood such for example salmon, tuna, and mackerel
  • Beef Liver
  • Mozzarella cheese
  • Mushrooms
  • Egg yolks
  • You may also get vitamin D from fortified foods. You can examine the meals labels to discover whether a meal has supplement D. Food that frequently has added calciferol include:
  • Milk
  • Breakfast cereals
  • Orange juice
  • Additional milk products, such for example yogurt
    Soy beverages
    Vitamin D is in many multivitamins. There are also vitamin D supplements, both in pills and a liquid for babies.

If you have vitamin D deficiency, the treatment is with supplements. Check with your health care provider about how much you need to take, how often you need to take it, and how long you need to take it.

Can too much vitamin D be harmful?
Getting too much vitamin D ( known as vitamin D toxicity) can be harmful. Signs of toxicity consist of nausea, nausea, reduced hunger, constipation, listlessness, and pounds loss. Excessive supplement D can also harm the kidneys. An excessive amount of supplement D also raises the amount of calcium in your bloodstream. Elevated levels of bloodstream calcium (hypercalcemia) could cause confusion, disorientation, and issues with heart rhythm.

The majority of instances of vitamin D degree of toxicity happen when somebody overuses vitamin D health supplements. Excessive sun exposure does not cause vitamin D poisoning because the body limits the amount of this vitamin it produces.

Supplement D warning: when should a person stop the supplements they are taking?

Vitamin D1.
VITAMIN D is important in managing crucial minerals in the body. During wintertime some individuals can take supplements to maintain their levels is high, however when should you stop using them? Specific symptoms can provide in the event that you have had in extra.

Supplement D helps control the quantity of calcium and phosphate within the body – nutrients that are necessary to keep bones, teeth and muscles healthier, so that it’s crucial to keep ones levels topped up. Due to the fact sun may be the primary supply of vitamin D, during the cold winter months, particular individuals could be susceptible to a supplement D deficiency. These consist of those who are not out-of-doors frequently or wear garments which cover up a majority of their epidermis. a supplement D deficiency can trigger symptoms such as for example exhaustion, bone and right back discomfort, depression and locks loss, so some individuals may give consideration to using vitamin D supplements.

During the cold winter months you should consider taking a supplement containing 10 micro-grams of vitamin D if you believe you’re not getting enough from food.

However the body usually gets enough vitamin D from normal sunshine and consuming foodstuffs such as for example egg yolks, liver, greasy seafood and red meat.

Using vitamin D over an extended time period can contribute to more severe problems.

Invest the vitamin D over an extended duration it may cause calcium to develop and result in harm from the renal, bones and heart.

If you are in the sunlight constantly your vitamin D levels is high and you should never forget to full cover up or protect the skin.

If skin appears to be subjected to sunlight for long amounts of time it could raise the risk of skin lesions and cancer of the skin.

Cancer of the skin appears to be brought on by ultraviolet light detrimental to the DNA in epidermis cells.

What’s generally not known can there be are a couple of kinds of skin cancer – melanoma cancer of the skin and non-melanoma skin cancer.