Scientists have finally nailed down one link between brain health and the “polar bear plunge.”

After many years of anecdotal evidence, scientists have finally nailed down one link between brain health and the “polar bear plunge.”

In a study associated with the #blood profiles of regular winter-time swimmers in London, Cambridge University researchers have identified a protein which was shown to slow the onset of #dementia in mice — and even repair a number of the damage brought on by the illness.

Their findings hinted at an explanation as to why hibernating animals, who lose 20% to 30% of these synapses during the cold winter to preserve energy, can regenerate those neural connections upon awakening in the spring.
Their findings hinted at a reason as to the reasons hibernating animals, who lose 20% to 30% of these synapses during the cold winter to preserve energy, can regenerate those neural connections upon awakening in the spring. (iStock)

For a long time, doctors have observed the healing and protective advantages of cold environments on individual ill patients but had yet to locate any connection.

If they revealed the role of a specific #protein — the RBM3 — in other mammals, such as bears, the #pathology behind its healing power began falling into place.

HEARING LOSS MAY CAUSE #DEMENTIA, STUDY FINDS

In a 2015 study published in the journal Nature, the Cambridge team discovered “cold-shock chemicals” during animal studies on healthy mice, mice with #Alzheimer’s, yet others with a prion, a neurodegenerative #disease. They observed that whenever healthy mice were placed into a hypothermic state — below 35 degrees Celsius — and then carefully rewarmed, they reap the benefits of a natural boost of RBM3. Once fully reanimated, researchers found the ordinary mice had also healed neurons that were harmed by the first shock.

Mice with Alzheimer’s and prion demonstrated neither effect.

However, in another test, scientists instead artificially increased RBM3 levels in the sick mice, then repeated the “cold-shock” process. This time around, the protein seemed to prevent vulnerable synapses — or cell connectors — from breaking, suggesting that RBM3 might shield the brain from #dementia diseases’ outcomes.

Their findings hinted at a description as to why hibernating animals, who lose 20% to 30% of their synapses during the cold winter to preserve energy, can regenerate those neural connections upon awakening into the spring.

During the time, Professor Giovanna Mallucci, who runs great Britain Dementia Research Institute’s Center at Cambridge, confessed to BBC Radio 4 Today listeners that the breakthrough study may end there as few human subjects would willingly submit themselves to hypothermia.

CORONAVIRUS ISOLATION KILLING A LARGE NUMBER OF ALZHEIMER’S PATIENTS

Those few, however, heeded the call of science. Martin Pate, a swimmer at Parliament Hill Lido in London, an outdoor pool open year-round, got in touch with researchers, volunteering himself and a little set of swimmers through the center — in the end, these were familiar with frigid temperatures.

People in a #Tai Chi group who practice near the pool were enlisted as a control group and not submitted to cold weather.

As researchers suspected, most swimmers, recovering from core temperatures as low as 34 degrees Celsius, showed notably high levels of RBM3 in contrast to the Tai Chi group.

COMMON SENSE OF SMELL MAY INDICATE LOWER RISK OF DEMENTIA IN OLDER ADULTS: STUDY

“If you slowed the progress of dementia by even a few years on an entire population, that could have an enormous impact economically and health-wise,” said Mallucci, who shared her recent, unpublished findings in a live panel on YouTube.

However, researchers cannot recommend ice baths as a safe treatment due to the inherent dangers of swimming in near-freezing temperatures. A “cold-shock” is sufficient to prompt a heart attack or stroke in patients with high blood pressure levels or cause a swimmer to reduce their coordination, resulting in drowning.

Reference
Cold water may be an effective defense against dementia …. https://www.foxnews.com/health/cold-water-may-be-effective-defense-dementia

Even with early treatment, HIV still attacks young brains, study says

Many children living with HIV today are in sub-Saharan Africa. While early antiretroviral therapy, or ART, has ensured less deadly outcomes for little ones managing and subject to HIV, studies show the HIV most likely will prohibit the brain. HIV may disrupt neurodevelopment, affecting how children learn, reason operates.

 To get some inspiration Michael Boivin, professor, and director of a Psychiatry Research Program within the Michigan State University College of Osteopathic Medicine, began to understand how HIV impacts children’s neuropsychological development inside a two-year longitudinal study, published in Clinical Infectious Diseases.

 the National Institute of Allergy and Infectious Diseases supported partially The investigation, part of the National Institutes of Health.

 Boivin, with his fantastic colleagues, tested the neuropsychological creation of three teams of children aged 5 to 11: those that acquired HIV and were treated with ART, those exposed but HIV-negative, and those who were never revealed. The analysis occurred at six study sites across four countries in sub-Saharan Africa to get a robust view of how HIV is affecting children within the region.

 To this point, it is the first well-validated, multi-site neuropsychological exploration of African school-aged children affected by HIV.

 What your researchers discovered through various assessments was that even dealing with early treatment and excellent clinical care, you can still find significant neuropsychological problems for children living with HIV.

“These children came straight into the study by using a deficit when compared with their counterparts,” Boivin said. “It stayed about the same across the three years, except in the most critical area: reasoning and planning. Regarding that specific test domain, the babies coping with HIV failed to progress.”

 The gap between infected and HIV-negative children grew inside the planning and reasoning area in the study period., these abilities are likely to blossom in the school-aged years in healthy children.

 “This is the most important cognitive function for the future of children managing HIV concerning their likelihood of taking their medications, making good decisions, abstaining from risky behaviors like early sexual activity, psychosocial issues, and school-related achievement,” Boivin said.

 Conclusions? Early medical treatment, started as far back half a year legal, will not be a sufficient amount to address the neurocognitive deficits linked to HIV, even though it help keep children alive cleanse that they would be without treatment. In these children, treatment ought to be started even earlier to strengthen long-term neurocognitive outcomes.

 “Our company will complement the long-term care and assist with actual behavioral interventions,” Boivin said.

 That’s something Boivin with his fantastic colleagues is performing work on. Only, Boivin received a 5-year, $3.2 million NIH grant to keep going he collaborated with children touched by HIV in Uganda and Malawi.

 Using this grant, researchers will investigate how MSU-developed computer cognitive games will serve as tools for neurocognitive evaluation, enrichment, and rehabilitation.

 Boivin hopes the fact that the results of each of the studies can help do this model of neuropsychological evaluation, a considered area of the cost-benefit.

Author Resource Box:

[Health] – Even with early treatment, HIV still attacks …. https://www.reddit.com/r/SDauto/comments/ecvozl/health_even_with_early_treatment_hiv_still/

Even with early treatment, HIV still attacks young brains …. https://www.sciencedaily.com/releases/2019/12/191218090208.htm

Admissions – College of Osteopathic Medicine – Michigan …. https://com.msu.edu/Admissions/index.htm

Do you know how you can make mindfulness a habit?

It’s estimated that 95%of our behavior utilizes autopilot. That’s because neural networks underlie our line of habits, reducing our many sensory inputs per second into easy shortcuts so we can function within this crazy world. These default brain signals can be so efficient that they will often trigger to relapse into old behaviors before we remember what it is that we meant to do instead.

Image result for mindfulness

Mindfulness is the exact opposite of such default processes. It’s executive control rather than autopilot and enables intentional actions, willpower, and decisions. But that takes practice. The more we activate the intentional brain, the stronger it gets. Every time we perform something deliberate and new, we stimulate neuroplasticity, activating our grey matter, which is full of newly sprouted neurons that have not yet been groomed for the “autopilot” brain.

But here’s the issue. While our intentional brain knows what exactly is most beneficial us, our autopilot brain causes us to shortcut our way through life. So just how is it possible to trigger ourselves to be mindful when we require it most? It is here that the notion of “behavior design” is available. It’s a way to put your intentional brain within the driver’s seat. There are a couple of methods to do that—first, slowing down the autopilot brain by putting obstacles within its way, the number two, removing barriers in the path of the intentional mind, therefore it can gain control.
Shifting the balance to provide your intentional brain more power takes some work, though. Here are a few ways to get started.

Put meditation reminders near you. If you intend to perform yoga as well as to meditate, put your yoga mat or your meditation cushion amid your floor. Therefore, you can’t miss it as you walk. Refresh your reminders regularly. Say you choose to utilize sticky notes to remind yourself of a new intention. That may function for a couple of weeks, however, your autopilot brain and old habits take over again. Try writing new notes to yourself; add variety, or make her funny. That way, they’ll stick with you longer. Create unique patterns. You could try a series of “If this, then that” messages to develop easy reminders to shift into the intentional brain. For instance, you might come up with, “If office door, then a deep breath,” as a change in means into mindfulness as you deal with to begin your workday. Or, “If phone rings have a breath before answering.” Each intentional action to shift into mindfulness will strengthen your conscious brain.

Author Resource Box:
https://www.mindful.org/how-to-meditate/

Childhood stress affects the brain when one becomes an adult

The human brain is a phenomenal body organ. It is responsible for ideas and emotions. It tells one’s muscles to move. It even can increase or decrease depending on what is occurring in ones setting. Now a brand new study discovers that going through severe instances as a kid also could have an influence. That stress can change the shape and shape of the human brain.

The adult brains of men and women who survived through lots of stress before the age of six — and then became despondent or anxious as young adults — were different than about older people who had a more carefree childhood. It seems that teens changed the shape of their brains by internalizing the pressures experienced years earlier — replaying those events in the head and keeping inside the emotions they induced.

Scientists already knew that the form and size of a child’s human brain could alter in responses to lots of stress. They also realized that adults were more likely to be depressed if, as children, they had been mistreated, was living in impoverishment, or faced other difficult times. Some scientific studies showed that these types of despondent adults had uncommon modifications in their brain contour. However, no one had tested whether the very early stress and later brain changes had been connected.

Meditation may protect your brain from aging

As we grow older we forget our keys or usually do not remember people’s names, or solve math problems less readily once we approach middle age. This is often described as age-related cognitive decline. Years ago, scientists thought that this decline was inevitable, but extraordinary research in past times two decades has shown that the adult brain changes with experience and training throughout the lifespan-a phenomenon referred to as neuroplasticity.

Epidemiological research finds that how a brain ages relies on a number of factors including diet, physical activity, lifestyle choices, and education. The healthier and more active one’s lifestyle, a lot more likely she or he will maintain cognitive performance with time. Meditation can be a vital ingredient for ensuring mind health and maintaining good mental overall performance. Recent study suggests about how mindfulness meditation practice might help keep aging brains fit and functional.

To keep up mental acuity, it is important to keep what researchers call your neural reserve in great working order. This “reserve” refers to your brain’s mental efficiency, capacity, or perhaps flexibility. Emerging evidence implies that the consistent mental teaching that develops in mindfulness yoga can help keep that “reserve” intact. As an example, one report about the evidence linked regular meditation with positive improvements in human brain function such as heightened attention, awareness, working memory, and greater mental efficiency.

Studies are showing that daily meditation impacts both brain “states” and brain “ networks. ” Brain state schooling involves activating large-scale systems inside the brain that affect an easy number of emotional and mental processes. Experienced meditators have higher concentrations of tissue in brain regions most depleted simply by ageing, suggesting that deep breathing practice may help to attenuate mind age and drive back age-related decline.

Meditation may provide another added benefit-increased mental versatility. For some, age come with a rigidity of thoughts, feelings and opinions, together with inability to flow aided by the challenges and obstacles which can be the main tide of life. Which can be a source of stress, and potentially even illness. Since most meditation practices emphasize developing a comprehension of thoughts, feelings, and physical sensations without creating a narrative or judgment concerning the experience, mindfulness mediation can help to lessen a person’s attachment to fixed outcomes, increase mental flexibility, and add to one’s neural reserve.

Although encouraging, it is imperative that you observe that this research is with its infancy and results are mixed. For example , numerous studies have stated that older meditators outperform age-matched non-meditators, or function comparably to younger participants on a number of interest tasks. Others have shown little or no change in cognitive function following a mindfulness intervention designed for old adults, or report that improvements are not maintained as time passes.

That which we can say for certain is that long-term engagement in mindfulness meditation may enhance intellectual performance on older adults, and therefore with persistent practice, these benefits might be sustained. That’s great news to obtain the scores of aging adults trying to combat the side effects of maturing on the mental faculties.

Science is moving forward in China, surgeons are treating addiction with brain implants

Deep brain stimulation (DBS), an experimental technology that involves implanting a pacemaker-like device in a patient’s brain to send electrical impulses, is a hotly debated subject in the field of medicine. It’s an inherently risky procedure and the exact effects on the human brain aren’t yet fully understood.

But some practitioners believe it could be a way to alleviate the symptoms of depression or even help treat Alzheimer’s – and now they suspect it could help with drug addiction as well.

In a world’s first, according to the Associated Press, a patient in Shanghai’s Ruijin Hospital had a DBS device implanted in his brain to treat his addiction to methamphetamine.Other studies in China have yielded mixed results trying to treat opioid addictions using DBS, according to the AP. In the United States, at least two studies that tried to treat alcoholism with DBS were dropped for not being able to justify the risks.

The idea of using DBS to treat drug addiction has raised concerns in medical communities across the globe – and not just concerning the inherent risks of a brain hemorrhage, seizures, infections, or personality changes.

Some researchers argue that the precise relationship between the technique and drug addiction are not yet known and require further study. Animal studies have shown some signs of its effectiveness, but remain inconclusive.The idea of using DBS to treat drug addiction has raised concerns in medical communities across the globe – and not just concerning the inherent risks of a brain hemorrhage, seizures, infections, or personality changes.

Some researchers argue that the precise relationship between the technique and drug addiction are not yet known and require further study. Animal studies have shown some signs of its effectiveness, but remain inconclusive.

Most useful health supplements of the brain: minerals and vitamins that increase the brain’s functions

Brain supplements2MENTAL PERFORMANCE is the most essential an element of the body, and choosing the best health supplement to guide mind function could improve quality of reasoning, creativeness, alertness, concentration, attention, memory or even temper.

The brain may be the greatest resource for efficiency and is the principle controller associated with bodies functionality. Once the mind experiences an overload of anxiety it actually changes the brain’s structure. Stress is considered the most typical reason behind alterations in mental performance and neuroscientists have found that chronic anxiety may cause fixed problems. In accordance with medical professionals a wholesome brain diet could be resolved with a handful of significant supplements and nutrients.

THE MIND is the most essential part of the body, and choosing the best supplement to support mind function could enhance quality of reasoning, imagination, alertness, focus, concentration, memory as well as mood.

The mind may be the ultimate device for productivity and it is the main controller regarding the systems functions. When the brain experiences an overload of anxiety it really changes the brain’s structure. Stress is the most common reason for alterations in mental performance and neuroscientists are finding that chronic anxiety may cause permanent harm. Relating to medical professionals a wholesome brain diet may be solved with a number of important products and vitamins.

Fish oil

These omega 3 essential fatty acids may take place in a lot of different basic cerebral functionality and stop the decrease of this mind.

Referred to as “brain meals” it can be found in particular types of fish in addition to health supplement.

Those who maximize their fish oil dose saw an enhancement with episodic memory, better reaction times and a much better performing memory.

Folic acid, supplement B6 and B12

These nutritional vitamins shield mental performance from intellectual decrease and lower mental performance atrophy. Folic acid has particular impacts on their intellectual purpose of mental performance. Good food sources include cereals, beans and fruits.

Vitamin D supplements

Supplement D has a crucial role at the beginning of life brain improvement and a deficiency of the supplement is of the increased risk of brain-related disorders such as Parkinson’s illness and autism.

The supplement takes on a crucial role in very early life mind improvement and aids mind performance.

The very best foods to improve the mind include:

  • Blueberries
  • Fatty seafood
  • Turmeric
  • Broccoli
  • Coffee
  • Chocolate brown Pea Nuts
  • Eggs

What’s best for the human body is similarly advantageous to the mind and the right nutrients and supplements may have an enormous enhancement to your intellectual cap capability, memory and feeling.