Tag Archives: cannabis

New study show that CBD might help people struggling with opioid addiction

New research out Tuesday may be the latest to declare that cannabis—or at least an essential ingredient of it—might assist people struggling with dependency. It found that people with opioid usage disorder experienced fewer problems of craving when presented cannabidiol, or CBD, over a placebo. CBD also helped them settle down and limited their stress and anxiety.

CBD is the part of cannabis that will not make us feel high (that is THC). It is already used to treat certain types of seizures, as a prescription drug authorized just a year ago called Epidiolex. However, there are lots of other advertised health advantages, such for instance stress reduction or protecting against dementia, which has helped sprout a cottage industry over CBD.

A whole lot of these products and statements are unlikely to become more than overhyped bunk. However, there has been some evidence showing that CBD might help using the opioid crisis. Some people are regularly using cannabis as a partial substitute for doctor prescribed opioid painkillers to handle their pain—a use that researchers may also need to study within the lab. Moreover, research elsewhere, including because of the current study’s authors, has shown that CBD can dampen the consequences of withdrawal and yearning in opioid-dependent animals which are taken off the drug.

The gold standard for testing whether or not something is doing what it is claimed to be doing is a double-blinded, randomized, and placebo-controlled scientific trial, however. So that is what the authors behind this study, published into the American Journal of Psychiatry, experimented with doing.

With regards to their trial, they recruited 42 gents and ladies who had been living with opioid use disorder, specifically heroin but were currently not using the drug. Half were randomly given pills containing CBD (actually just Epidiolex), in 2 dosages, although the rest took a placebo. Then, throughout per week, the volunteers needed to watch three-minute long videos either containing nothing but neutral graphics, like nature sounds, or videos featuring drug paraphernalia like syringes or bags of powder meant to appear to be heroin. The 2nd set of videos, it was thought, will make the volunteers crave the drug and/or anxious.

The test subjects were given CBD for three days. Also, they were tested for post-video craving and anxiety symptoms just after they took a pill, every single day after a CBD session, and per week after the last session. Across these situations, the researchers found, people on CBD reported less craving and anxiety an average of than the placebo group, while objective measurements like heart rate and cortisol levels in saliva (often utilized to indicate acute stress) were also lower.

Does CBD help with anxiety?

CBD has more than 100 chemical compounds. The compounds are in the cannabis plant. CBD is a very close chemical counterpart of tetrahydrocannabinol or THC. In fact, the two chemicals are detached by the arrangement of a distinct atom. Though, there is one main alteration amongst the two: THC gets you high, even though CBD cannot.

The CBD that is sold to consumers is a hemp-derived product, which legally cannot have any more than 0.3 percent THC. Translation: No matter how much the person consumes, the individual will not get high from CBD.
Though the research is in its early stages, CBD is supposed to alleviate anxiety by aiding the body in processing serotonin, a hormone, and neurotransmitter that functions to regulate one’s emotions. The process is similar to that of serotonin reuptake inhibitors (SSRI), a class of anxiety and depression medicines.

SSRIs target a serotonin receptor known as 5-HT1A and upsurge the availability of serotonin in the brain to aid in boosting a person’s mood.
Similarly, a 2019 research study found that CBD heightened 5-HT1A transmission in rats and lessened “anxiety-like behavior.” Now, it’s up to investigators to exam this outcome on human being also.

Did you know that marijuana munchies do not make you fatter ?

Marijuana could cause the munchies, or even it may not. The only real fact here’s that pot smokers weigh less than their non-indulging peers, groundbreaking research at the University of Michigan provides indicated.

So many things certainly are an issue of faith, from the sanctity of scripture to your pets understanding English. Now technology has debunked a dearly kept belief of the corpulent cannabis customer that the drug causes compulsive consuming, which explains why they’re fat. If non-users wonder why people would smoke marijuana, inquire any user.

This is not a pot dream. The study was published on the night time of Passover in the prestigious, Oxford-published Global Journal of Epidemiology. Moreover, if the users had been newbies or persistent indulgers, these were found to become less inclined to be obese or obese overall.

The differences weren’t main: 900 grams for participants 170 centimeters high who weighed 91 kilograms at the beginning of the study, 2 pounds for 5-foot-7-inch participants weighing about 200 pounds.

However the variance was shared amongst the total sample size, the experts write, which isn’t a report on a few isolated villages of mutants. It had been predicated on body mass information from 33,000 individuals in the U.S. National Epidemiologic Study of Alcoholic beverages and Related Conditions.

Many, though not all, aficionados of weed will verify post-smoking food cravings, usually sweet. The simple truth is that neither Alshaarawy nor anybody else includes a clue why this occurs. Also why some individuals get the munchies plus some don’t. Alternatively, why on the planet marijuana customers would weigh significantly less than their peers.

In the news, independent research by the Complutense University of Madrid and released in Forensic Science International reported on disturbing levels of human being feces in hashish in love with Spanish streets. Provided their description, there is no cause to assume, as well as wish, that this is a Spanish aberration.

Now, it is correct they didn’t examine more than 30,000 samples; they examined 90 that they had purchased on the roads of Madrid. Also, they found discrepancies between your fecal content material of hash bought using small bricks that they are charmingly known as ingots or “acorns.

As though that were not enough, the majority of the hash bought from medication sellers was found to be contaminated by E. coli nevertheless, which begs the query of what E. coli, part of the standard intestinal flora, will to one’s lungs. It could trigger pneumonia, among other activities.

It is interesting that California has turned to Israeli for Medical Marijuana Research

When Israeli plant researchers Nirit Bernstein got a call five years ago from a research institute requesting if she had be interested in working on the cultivation of medical cannabis. But then a thought quickly crossed her mind.

Bernstein studies whole-plant cannabis at Israel’s state-run Volcani Institute and was one of several experts in various fields, including science, medicine and business, who met in San Francisco May 1-2 for the inaugural CannaMed/Tech Summit, produced by the California Israel Chamber of Commerce.

While there is much hope and optimism about healthcare cannabis, there are also many questions – and businesses and investors in California and the U.S. are relying on Israel for some of the answers. It’s easier to learn about the multifaceted plant in Israel, which not only allows research but also funds it, unlike in the U.S., where strict federal laws are an impediment to clinical studies.

Hebrew University’s Multidisciplinary Center for Cannabinoids Research, for example, is studying possible applications for drugs targeting cancer, migraines, inflamed tissue, stress, pain and renal disease.

At Volcani, Bernstein is focusing on how to use light, heat, fertilizer and growing conditions to standardize the compounds in cannabis. (The best-known are usually THC and CBD, both first isolated by Israeli pharmacologist Raphael Mechoulam in the mid-1960s.) She said growing cannabis on a large scale is much more difficult than raising a conventional farm crop.

In cannabis grown by small farmers, the active substances are not always consistent – they can be stronger at the top of the plant, or vary from plant to plant. Bernstein stated it would be like giving a patient different amounts of aspirin and never telling the person the dosage.

Further complicating the issue of dosage is drug delivery, or how the active elements of cannabis get into the body, whether taken intravenously, orally or through smoking, said Professor Simon Benita from the School of Pharmacy at Hebrew University.

A host of factors makes it especially difficult to study these issues in the U.S. While the use of recreational and medical cannabis is legal in California, researchers who want to conduct medical trials still have to deal with restrictive federal rules, mentioned Donald Abrams, an oncologist at UCSF Medical Center and SAN FRANCISCO BAY AREA General Hospital.

So far, the FDA has approved only one drug using cannabis compounds: Epidiolex, which treats epilepsy. The rest of the products sold in California and other states where healthcare marijuana is lawful are handled more like vitamins or supplements, subject to fewer regulations. What manufacturers and sellers promise may be heavy on the marketing and light on the science. But patients and doctors alike are still turning to the plant for its reported healing properties.

The demand for medical cannabis makes Israel an important partner for businesses wanting to join the green boom, one of the goals of CICC’s executive director Sharon Vanek, who initiated the conference. Attendee Boris Shcharansky, chief operating officer for wellness company Papa & Barkley, said his company had turned to Israel to conduct product research without all the red tape of the U.S.

Until U.S. regulations and attitudes change, companies and health professionals will continue to seek Israeli expertise on the eco-friendly plant, partnerships that the California Israel Chamber of Commerce is encouraging.

Already, many see Israel as the place to go for advanced information on medical marijuana.

Marijuana users less likely to be overweight, obese

 

shallow focus photography of cannabis plant
Photo by Michael Fischer on Pexels.com

Brand-new investigation discovers that, regardless of the wide-spread sensation of experiencing “the munchies” immediately after using pot, cannabis users are inclined to ponder much less and they are not as likely to become heavy.

New study discovers an amazing connection concerning pot use and reduce excess fat.

Latest studies calculate the fact that more than 22 million citizens in the United States age range 11 and above on a regular basis work with cannabis and that a growing number of men and women and elderly people are taking up one of the behavior.

The majority of the adults who have ingest marijuana on a regular basis do this for leisurely reasons. Nearly 90 percent of United. S. adult cannabis owners declare they use it recreationally, while only the remaining 10 % use it for therapeutic reasons.

Among the physiological effects of pot is an increased hunger, or what is actually commonly known as getting the hunger pains.

Even though it might appear user-friendly that an raised hunger could result in putting on weight, recent well known epidemiological research declare that marijuana users are much less likely to be heavy.

So , some group of experts via Michigan State University (MSU), in East Lansing, attempt to research this subject additionally, examining whether individuals that on a regular basis ingest marijuana are more inclined to put on weight.