Tag Archives: Health

Behavioral Science, disease, Health, mental health, Public health

How do muscle contractions and the chemical signals they release contribute to the development of brain networks?

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The discovery that muscle contractions release chemical signals that promote brain network development provides valuable insights into the intricate link between physical activity and cognitive function. It sheds light on the molecular mechanisms underlying the observed cognitive benefits of regular physical exercise, especially in the context of age-related cognitive decline and neurodegenerative diseases like Alzheimer’s. The brain is a highly dynamic organ, and these findings suggest that physical activity may support its plasticity and resilience through these muscle-derived signals, thus playing a key role in preserving cognitive function as we age.

This newfound understanding of the role of muscle contractions in brain development has substantial implications for therapeutic strategies and exercise recommendations. Conditions where brain network development is compromised or slowed, such as in certain developmental disorders or following brain injuries, could potentially benefit from tailored physical activity programs designed to stimulate muscle contraction and hence, release of these beneficial chemical signals. This approach may contribute to neural repair and reorganization, aiding recovery and supporting cognitive function in these individuals.

This research not only expands our biological understanding but also underscores the potential value of physical exercise in clinical settings. It provides a strong rationale for the integration of regular physical activity into therapeutic regimes, not just for its well-known cardiovascular benefits, but also for its potential neuroprotective effects. Further research is needed to identify the most effective types and intensities of exercise for different patient groups, but the existing findings clearly highlight the role of physical activity in brain health and development.

Resource

Rodríguez‐Valentín, Rocío, Ignacio López‐González, Ramón Jorquera, Pedro Labarca, Mario Zurita, and Enrique Reynaud. “Oviduct contraction in Drosophila is modulated by a neural network that is both, octopaminergic and glutamatergic.” Journal of cellular physiology 209, no. 1 (2006): 183-198.

Fagerlund, M. J., and L. I. Eriksson. “Current concepts in neuromuscular transmission.” British journal of anaesthesia 103, no. 1 (2009): 108-114.

Woolf, Nancy J., and Larry L. Butcher. “Cholinergic systems mediate action from movement to higher consciousness.” Behavioural brain research 221, no. 2 (2011): 488-498.

disease, drugs, Health, Long Covid Symptoms, Public health

Are individuals with low levels of vitamin D at an increased risk of developing long COVID?

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Recent research presented at the 25th European Congress of Endocrinology has suggested that low vitamin D levels may increase the risk of developing long COVID. This is a condition where the symptoms of COVID-19 persist for more than 12 weeks after the initial infection. The study looked at 100 patients with and without long COVID and found that those with long COVID had lower levels of vitamin D. This correlation was particularly evident in patients who experienced symptoms like confusion, forgetfulness, and poor concentration. While more research is needed to confirm the link, scientists are exploring whether vitamin D supplements could help reduce the risk of long-term COVID and improve its symptoms.

Long-term COVID risk may increase with low levels of vitamin D. https://www.news-medical.net/news/20230513/Long-COVID-risk-may-increase-with-low-levels-of-vitamin-D.aspx

The Vitamin D Society. http://vitamindsociety.org/

Post-COVID-19 condition (long COVID) – Canada.ca. https://www.canada.ca/en/public-health/services/diseases/2019-novel-coronavirus-infection/symptoms/post-covid-19-condition.html

LONG COVID LINKED TO VITAMIN D DEFICIENCY. http://www.cachehosting.com/news/other/long-covid-linked-to-vitamin-d-deficiency/ar-AA1baMoE

Diet, education, Health, Healthy eating, Public health

Are current dietary recommendations for cardiovascular health facing challenges in light of emerging evidence regarding the impact of saturated fatty acids on the levels of low-density lipoprotein cholesterol (LDL-C) and lipoprotein A (Lp(a))?

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A recent perspective piece published in The American Journal of Clinical Nutrition delved into the current dietary recommendations aimed at reducing the intake of saturated fatty acids in order to mitigate the risk of cardiovascular disease.

The article shed light on the impact of lower saturated fatty acid intake on low-density lipoprotein cholesterol (LDL-C) and lipoprotein A. While dietary modifications have garnered significant attention in cardiovascular disease prevention, the effectiveness of replacing saturated fatty acids with alternative options remains unclear. Recent studies have shown that while reducing saturated fatty acid intake lowers LDL-C levels, it leads to an increase in lipoprotein A levels, which is associated with an elevated risk of cardiovascular disease. Lipoprotein A has been identified as an independent risk factor for atherosclerosis-related cardiovascular disease. Although genetic factors primarily regulate lipoprotein A levels, certain non-genetic factors, including dietary saturated fatty acid intake, contribute to its increase. Replacing saturated fatty acids with carbohydrates or monounsaturated fatty acids does lower LDL-C levels but also results in a concurrent increase in lipoprotein A levels. This finding calls for further research and better clinical practices to monitor the effects of dietary changes on lipoprotein A and LDL-C levels. Additionally, assessing cardiovascular disease risk accurately may require measuring LDL-C independently of lipoprotein A cholesterol content or including an evaluation of lipoprotein A cholesterol content. The study suggests that individualized dietary recommendations tailored to lipid profiles and considering additional cardiac health markers, such as lipoprotein A cholesterol content, may be necessary for effective disease prevention.

Dietary Recommendations For Cardiovascular Health Challenged By New …. https://primenewsprint.com/health/dietary-recommendations-for-cardiovascular-health-challenged-by-new-evidence-on-saturated-fatty-acids-effects-on-ldl-c-and-lpa-levels/

disease, drugs, Health, Public health

What You Should Know Regarding Monkeypox?

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Thousands of people have contracted monkeypox throughout the United States. The spread has been designated as an epidemic, which naturally arouses public concern. Discover who is at danger and how we can protect ourselves, our community, and our loved ones.

How does monkeypox spread?

It is essential to realize that viruses are not selective. They want just a host. The same holds true for monkeypox as for any other virus. To help reduce the spread of monkeypox, we must first eliminate its stigma. Anyone, regardless of age, gender, race, or sexual orientation, is vulnerable.

It is evident that monkeypox is transmitted by direct skin-to-skin contact. Identifying and reducing high-risk behaviors and settings is the most effective method of disease prevention.

According to the Centers for Disease Control and Prevention (CDC), the following behaviors enhance the likelihood of acquiring monkeypox:

  • Close contact with a person or individuals who have been diagnosed with monkeypox or with a person or persons who have a rash that resembles monkeypox.
  • Close or close personal contact with people infected with monkeypox in a social network. Social networks might include individuals met at pubs, parties, on websites or via apps.
  • Sexual contact or intimate behavior with several partners in places where monkeypox is known to occur.
  • Within 21 days after sickness start, travel outside the United States to a nation with confirmed cases of monkeypox or where monkeypox is endemic.
  • Occupational exposure to monkeypox or other orthopoxviruses, such as testing laboratory personnel or some public health personnel. In these situations, the right use of personal protective equipment will aid in reducing danger.

How can I reduce my infection risk?

As with any infectious illness, the pillars of infection prevention and control may be applied: When you are unwell, you should wash your hands, avoid touching your eyes, lips, and face, and avoid contact with others. Avoid prolonged physical contact, contact with respiratory secretions, and contact with products or textiles used by someone with monkeypox to reduce your chance of developing the disease.

Is a monkeypox vaccination available?

Kansas City has provided the University of Kansas Health System with a restricted amount of vaccination doses. The health care system administers vaccinations to people who fulfill the qualifying requirements. Currently, the CDC advises immunization against:

People who are aware that a sexual partner has been diagnosed with monkeypox during the preceding 14 days.

Individuals who have had several sexual partners in the preceding 14 days in an area where monkeypox is known to exist.

Individuals who have reported any of the following during the preceding 14 days:

  • Sex with numerous partners or multiple partners.
  • Sex at a commercial sex venue or in conjunction with an event, location, or specified geographic region where transmission of monkeypox has been recorded.
  • We are devoted to providing everyone with high-quality care. If you are a current patient of the health system and feel you fulfill any of the eligibility requirements, contact your primary care physician or provider (by phone, text message, or MyChart message) for further information.
  • We must collaborate to eliminate the stigma associated with this condition and prioritize wellness. We highly urge persons at high risk or who are worried to communicate honestly with their healthcare professionals.
disease, Health, Public health

Did you know that unvaccinated are 14 times more likely to get monkeypox, data from eligible shot recipients shows?

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Those who have not had the vaccine for monkeypox are 14 times more likely to get the illness than those who have, according to fresh, but limited, statistics released by the Centers for Disease Control and Prevention on Wednesday morning.

The sampled population consists of males who engage in sexual behavior with other men or persons with several sexual partners. The figures provide our first glimpse at how effectively the JYNNEOS vaccine, the most effective method of protection against monkeypox, functions in the real world.

At a briefing on monkeypox held at the White House on Wednesday, CDC Director Rochelle Walensky said, “These new data give us cautious comfort that the immunization is functioning as planned.”

Dr. Demetre Daskalaskis, the White House’s deputy response coordinator for monkeypox, requested that individuals disseminate the “early good news.”

He said that “information is power” and that it empowers people to make health-related decisions with more knowledge and confidence.

What caused the dramatic reduction in monkeypox cases in the United States?

Since the beginning of the current outbreak, there has been little information on the effectiveness of the JYNNEOS vaccine, which was initially designed to combat smallpox.

Since the outbreak began in May, the Food and Drug Administration, the Centers for Disease Control and Prevention, and the National Institutes of Health have conducted many studies into the safety and effectiveness of the JYNNEOS vaccine, mostly at the request of LGBTQ community activists.

Walensky also observed that the new data is only a glimpse, while being optimistic. Concerning the extent of JYNNEOS’s protection, several questions remain unresolved.

For instance, the new vaccination efficacy rate was not predicated on two doses given 28 days apart. Instead, it relied on information gathered two weeks after the first shot.

Even though the majority of federal public health experts advocate two doses, the CDC has not yet provided information on the effectiveness of the vaccine after all doses have been administered.

“These early results, together with similar findings from studies undertaken in other countries, suggest that even a single dose of the monkeypox vaccine gives at least some initial protection against disease. In spite of this, laboratory studies have shown that immune protection reaches its peak two weeks following the second vaccination dose, or “Wednesday,” as Walensky said.

She said, “Because of this, we continue to recommend that individuals get two doses of the JYNNEOS vaccine, 28 days apart, in order to provide robust, long-lasting protection against monkeypox.”

According to Walensky, further study is being conducted on the efficacy of two dosages.

The CDC has not yet separated the efficacy data for various injection techniques to see whether there are any differences between the current approach, in which a lower dosage is injected just beneath the skin, and the earlier way, in which a deeper injection is administered.

Also unclear is the extent to which changes in behavior might influence the effectiveness of the vaccination results.

If vaccinated individuals have fewer sexual partners and possibilities for skin-to-skin contact, they may be less likely to get monkeypox.

Eliminating monkeypox is feasible, according to experts, but containing the disease remains challenging.

According to Walensky, a key lesson from COVID-19 is that the CDC intends to make all of its existing data accessible in real time as soon as it becomes available, even while additional data are on the way.

“Through a portfolio of vaccine effectiveness programs, [the] CDC will continue to analyze how well these immunizations are functioning in the continuing outbreak. These endeavors will assist us in determining the extent and duration of the protection provided. “We’ll continue to provide you with further details as they become available,” Walensky added.

Even though the JYNNEOS vaccine is not yet approved for use by the general public, the CDC is expanding the number of at-risk Americans who are eligible to get vaccination against monkeypox.

The inclusion now includes gay or bisexual men who have had one recent romantic relationship or who have just received a new diagnosis of one or more STDs. It also includes sex workers.

Although many states and jurisdictions have already expanded eligibility, the CDC’s latest step puts it more in line with regional guidelines.

Diet, Fitness, Health, mental health, Public health

Do you think that persons who experience anxiety and depression could benefit from taking vitamin B6?

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According to recent research, vitamin B6, a popular vitamin supplement, may benefit those who suffer from anxiety and depression. However, in the UK, researchers recruited 478 participants with anxiety or depression and randomly allocated them to receive high dosages of vitamin B6, vitamin B12, or a placebo. They then evaluated the subjects before and after they had taken the tablets for a month. Compared to those taking a placebo, those taking the B6 supplement reported significantly fewer symptoms of anxiety and depression. They conclude that some people may be able to prevent the adverse effects of prescription drugs by taking vitamin B6 supplements. However, with your doctor first before beginning a new supplement.

disease, Health, Public health

What do you think of a meningococcal disease epidemic in the US that has claimed the lives of 25% of those affected this year?

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According to the director of the Florida Department of Health, 48 instances of meningococcal disease were reported in Florida in 2022, and 12 of those cases resulted in fatalities. Neisseria meningitidis, a bacteria that can infect the brain and spinal cord lining, is the culprit behind the sickness.

As opposed to the flu or common cold, it is less communicable. The monkeypox outbreak, which primarily harms gay males but is not a “gay disease,” is coinciding. The general populace in America needs to prepare for an impending new wave of illnesses.

Culture, Education, education, equal rights, Ethics, government, human rights, Politics, Public health, Science, Social Justice, White House

Did you know that there will likely be further demonstrations this weekend in response to the agony and anger caused by the Supreme Court’s decision about abortion?

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According to authorities, tear gas was deployed to disperse protesters outside the Arizona State Capitol. Numerous protestors gathered in New York City’s Washington Square Park to oppose the judgment. Anti-abortion protestors were there, although they maintained a low profile. Following the demonstration, at least 20 individuals were “taken into jail with charges pending” throughout the city. In 2019, the biggest proportion of abortions performed on women requesting the procedure were performed on black women.

According to the statistics, they also had the highest abortion rate, with 23,8 abortions per 1,000 women. Black women who are pregnant or have just given birth are three to four times more likely to die than White women in the same circumstances. Friday, after the Supreme Court reverses Roe v. Wade, anti-abortion groups protest in Washington, D.C. Champagne is consumed by anti-abortion activists in front of the Supreme Court. Rachel Herring, an anti-abortion campaigner, said, “According to Judaism, life starts with the first breath, when the soul enters the body.”

Following the Supreme Court’s decision to overturn Roe v. Wade, supporters for abortion rights pound on the doors of the Arizona State Senate. On Friday, June 24, anti-abortion demonstrators celebrate in front of the US Supreme Court in Washington, DC. An anti-abortion activist wears socks that proclaim “abortion is cruel” while arguing with an abortion rights activist. On Friday, Jill McElroy and her nine-year-old daughter Meriam joined in an abortion rights rally in front of the Supreme Court. She stated, “A lesson we have always taught our children is that they are the masters of their own bodies, and the Court’s ruling today goes against that, and as a family, we believe that’s wrong.”

Champagne is consumed by anti-abortion activists in front of the Supreme Court. I was there at the moment the decision was made. I am delighted. Earlier, I was walking on air, says pro-life activist Noah Slayter. Friday, the phrase “Our bodies, our choices” is spray-painted on a temporary wall in Washington, D.C.

Following the Supreme Court’s decision to overturn Roe v. Wade, pro-choice protestors pound on the doors of the Arizona State Senate on Friday. Outside the U.S. Supreme Court on Friday, an anti-abortion protester wears socks that proclaim “abortion is cruel.” In Arizona and Arkansas, abortion providers have began discontinuing their services. Dr. DeShawn Taylor remarked that she anticipates a period of darkness, albeit hopefully not for too long.

Approximately twenty abortion appointments originally planned for Friday through next week were canceled by Taylor’s facility. The head of Planned Parenthood said, “The majority of patients were desperate or scared” before to Friday’s Supreme Court ruling on abortion availability in certain states. A new legislation in California shields anybody conducting, helping, or receiving an abortion from any prospective civil action originating from outside the state. A clinic owner in Mississippi said that a woman should not have to leave the state to get medical treatment.

disease, drugs, Health, Public health

Did you know that women are more likely to suffer from long-term COVID, highlighting the crucial need for sex-specific research?

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A recent study published today in the journal Current Medical Research and Opinion finds that girls are “significantly” more likely than men to suffer from protracted COVID and will exhibit dramatically distinct symptoms.


Long COVID is a condition in which problems continue for more than four weeks after the initial COVID-19 infection, and in some cases for many months.


Researchers from the Johnson & Johnson Office of the Chief Medical Officer Health of Women Team analyzed data from approximately 1.3 million patients and found that females with long COVID exhibit a variety of symptoms, including ear, nose, and throat issues; mood, neurological, skin, gastrointestinal, and rheumatological disorders; and fatigue.


However, male patients were more prone to developing endocrine problems, including diabetes and renal disease.


The authors explain that understanding the fundamental sex differences underlying the clinical manifestations, disease progression, and health outcomes of COVID-19 is essential for the identification and rational design of effective therapies and public health interventions that are inclusive of and sensitive to the potential differential treatment needs of both sexes.


Differences in immune system function between men and females may be a significant factor in determining sex differences in extended COVID syndrome. Females generate more rapid and potent innate and adaptive immune responses, which may shield them from the severity of acute illness. This difference, however, may make females more vulnerable to autoimmunity-related disorders that last longer.


As part of the review, researchers limited their search for scholarly articles to those published between December 2019 and August 2020 for COVID-19 and between January 2020 and June 2021 for long-term COVID syndrome. The overall sample size for all publications evaluated was 1,393,355 distinct people.


Even though there were a lot of participants, only 35 of the 640,634 articles gave enough information about the symptoms and effects of COVID-19 illness by gender to understand how girls and boys experience the illness differently.


Findings indicate that female patients were significantly more likely to have mental problems such as sadness, ear, nose, and throat symptoms, musculoskeletal discomfort, and respiratory symptoms at the outset of COVID-19. On the other hand, men were more likely to have kidney diseases called renal diseases.


The authors remark that this literature review is one of the few that breaks down by sex the particular health issues associated with COVID-related disease. Numerous studies have investigated gender disparities in hospitalization, ICU admission, respiratory support, and death. When it comes to sex, however, studies on the exact diseases induced by the virus and its long-term harm to the body have been inadequate.


The authors note that during earlier coronavirus epidemics, sex variations in outcomes have been recorded. Therefore, disparities in SARS-CoV-2 infection outcomes between men and women may have been predicted. Unfortunately, the vast majority of studies did not examine or report granular data by sex, limiting sex-specific clinical insights that may influence therapy. ” Even if it wasn’t the main goal of the researcher, sex-disaggregated data should be made public so that other researchers can use it to look into differences between the sexes that are important.


The research also identifies complicated aspects deserving of further investigation. Notably, women are more likely to be exposed to the virus in particular occupations, such as nursing and teaching. There may also be differences in who can get care based on gender, which could change how the disease naturally progresses and cause more problems and side effects.


The latter acts as a rallying cry: availability of sex-disaggregated data and deliberate analysis are necessary if we are to guarantee that unequal disease course outcomes are addressed. No study is complete until the data is made accessible to anyone who wants to answer the question, “Do sex and gender matter?”

Diet, disease, Fitness, Health, Healthy eating, Public health

Would you like to hear that a new study links coffee consumption to a lower risk of death?

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During the trial period, individuals who had moderate quantities of coffee, even with a little sugar, were 30 percent less likely to die than those who did not consume coffee.

Aileen Son for The New York Times

Researchers analyzed coffee consumption data obtained from the U.K. Biobank, a vast medical database including health information on the whole nation’s population. Three to five cups of unsweetened coffee per day was associated with the lowest mortality risk. Inconclusive were the data for persons who consumed coffee with artificial sweeteners. Other lifestyle factors, such as a healthy diet and frequent exercise, may also contribute to a reduced risk of death.

Coffee users may pick cold brew or drip coffee over less healthy caffeine sources, such as energy drinks or soda. Coffee beans have high quantities of antioxidants, which may help neutralize cell-damaging free radicals. Over time, an accumulation of free radicals may induce inflammation in the body, which can contribute to the formation of plaque associated with heart disease. Those who drank more than 4.5 cups of coffee each day had diminishing benefits.