No single food regimen works well with everyone. New research is one of comprehensive effort yet to understand why.

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A decade ago, spurred by the success of the Human Genome Project and the affordability of genetic sequencing, scientists started to explore the promise of “nutrigenomics.” Could personalized nutrition, informed by understanding of an individual’s DNA, assist in preventing and even
treat diet-related diseases?

The outcome of early studies from Harvard, Stanford and elsewhere were compelling: Genetic differences did actually predispose individuals to lose different levels of weight on different sorts of diets. A multimillion-dollar industry soon sprang up, premised on marketing DNA-based diets. But subsequent studies have failed to demonstrate any statistically significant difference between fat reduction between overweight individuals who “eat suitable for their genotype” and the ones that do not.

In fact, the result of genes on obesity has been hard to tease out; various studies put the figure at anywhere from 35 to 85 percent. Nutritionists have traditionally observed that no body weight-loss strategy works well with everyone, and that individuals show striking differences in their responses to different diets.

Reference
Diet for One? Scientists Stalk the Dream of Personalized …. https://monohealthy.com/diet-for-one-scientists-stalk-the-dream-of-personalized-nutrition-the-new-york-times/